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  • Ahmet Gözer
  • Onur Bahan
  • İshak Gökçek
  • Ufuk Kaya
  • Gökhan Uyanık
  • Gökhan Doğruer


Cat, ovariohysterectomy, oxidative stress


This research aimed to study the short-term effect of ovariohysterectomy on oxidant/antioxidant status in healthy cats. Twenty-two female cats were allocated to the present study. All the cats were anesthetized with the xylazine-ketamine and spayed. Blood samples were collected before (D0) and three and ten days after the ovariohysterectomy to determine serum malondialdehyde, glutathione, catalase, and glutathione peroxidase concentrations. There was a statistical increase in MDA concentrations on Day 3 compared to Day 0 (p<0.05). There were no statistical differences in the MDA concentrations between Day 3 and Day 10. Catalase activity showed a remarkable increment on Day 3 compared to Day 0 and then a declination on Day 10 compared to Day 3 (p<0.05). Glutathione activity was greater on Day 3 and Day 10 compared to Day 0. Glutathione peroxidase activity was decreased on Day 3 compared to Day 0 and then increased on Day 10. Nevertheless, these increases were not significant. In conclusion, this study clearly showed that ovariohysterectomy surgery resulted in oxidative stress within the first three days after ovariohysterectomy and oxidative stress disappeared ten days after ovariohysterectomy.


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How to Cite

Gözer, A., Bahan, O., Gökçek, İshak ., Kaya, U., Uyanık, G. ., & Doğruer, G. (2023). SHORT-TERM EFFECTS OF OVARIOHYSTERECTOMY ON SOME ANTIOXIDANT PARAMETERS IN CATS. Journal of Applied Biological Sciences, 17(3), 432–439. Retrieved from