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  • Purva Mishra Assistant Professor, ITM university, Raipur
  • Aditi Niyogi Poddar
  • Shivani Gupta


Chronic exposure, Cat fish, fluoride, accumulation, depuration


One of the major ground water pollutants is Fluoride, which is contributed in the environment by both natural (geogenic) and anthropogenic means. Fluorine is an essential element for living organism. Chronic exposure study of 60 days was carried out in model fish, Clarias batrachus, where the fishes were divided into three groups; control (Group I), 10 mgL-1 (Group II) and 20mgL-1(Group III) NaF.In a regular interval period of 15 days, accumulation status were reported in biological tissues. Maximum fluoride accumulation was found in Bone followed by liver, kidney, muscle and blood. After exposure of fishes to NaF for 60 days, depuration pattern was studied in group II and group III. Fishes from exposed groups were transferred to clean water, for a period of 20 days. Maximum depuration was observed in liver tissues followed by muscle, bone, kidney, blood. Depuration in group III was in the order; liver followed by kidney and muscle, bone and blood.


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How to Cite

Mishra, P., Poddar, A. N., & Gupta, S. (2023). TOXICOKINETICS PATTERN OF FLUORIDE IN CAT FISH, CLARIAS BATRACHUS. Journal of Applied Biological Sciences, 17(3), 440–450. Retrieved from